In all analyses statistical significance was set at p < 0

Within the Fig

Salt sensitive: Participants with SBP being at least 5 mmHg higher after HS intake compared to the values after the LS intake; Salt resistant: Participants whose SBP differed by <5 mmHg between HS and LS intakes; Independent variables: Urinary Na + , Urinary K + and Na + :K + excretion ratio; Dependent variable: SBP; Categorical variable: Participants were categorized into groups on the basis of increments of 1 g/day in urinary Na + and K + excretion to evaluate the linear trends

Mathematical research

Generalized linear habits was indeed utilized for linear regression research (Pearson’s R relationship) to assess the new organization out-of urinary Na + and you can K + excretion that have SBP. To possess Figs. dos and you can step three, two-way ANOVA having Tukey’s blog post hoc is performed to compare SBP among teams laid out based on urinary Na + and you will K + excretion. To measure the effectiveness of expanding urinary Na + and you can K + removal in line with SBP, Cohn’s Feeling Dimensions was computed. In the Figs. cuatro and 5 general Pearson’s R correlation is performed to assess the new organization of your urinary Na + :K + removal ratio that have SBP. six studies was indeed examined from the a great three-method ANOVA and the pairwise evaluations were made playing with Tukey’s blog post hoc decide to try. 7 relative frequency delivery was assessed using a beneficial Gaussian fit study. 05 (GraphPad prism application, type 8). Studies was showed given that suggest ± SD.

Baseline systolic blood pressure (SBP) at screening on regular diet (a) according to changes sodium excretion of <5 g/day, in salt sensitive (n = 154) and salt resistant (n = 180) group, slope of the for salt sensitive group is indicated for the sodium excretion ranges of <2–2.99 g/day, 3–3.99 g/day and 4–4.99 g/day (b) Correlation of baseline SBP (dependent variable) across the entire range of urinary sodium excretion (independent variable), (Pearson's R 2 for salt sensitive = 0.02 and for salt resistant = 0.02), in salt sensitive (n = 186) and salt resistant (n = 222) individuals.

Baseline systolic blood pressure (SBP) at screening on regular diet (a) according to changes potassium excretion for salt sensitive (n = 186) and salt resistant (n = 222) group, slope for salt sensitive and salt resistant group is indicated for the potassium excretion range <1–1.99 g/day, values shown as mean ± SD. b Correlation of baseline SBP (dependent variable) across the entire range urinary potassium excretion (independent variable), (Pearson's R 2 for salt sensitive = 0.001 and salt resistant = 0.008), in salt sensitive (n = 186) and salt resistant (n = 222) individuals.

Standard SBP in line with urinary salt in order to potassium excretion proportion (Na + /K + ) (a) correlation away from standard SBP (centered variable) over the whole directory of urinary Na + /K + removal (independent adjustable) , (Pearson’s Roentgen dos to possess salt sensitive and painful = 0.0004 and you will salt resistant = 0.0016) (b) baseline SBP considering alterations in sodium excretion and you may potassium removal variety inside the salt delicate (letter = 186) and salt unwilling (letter = 222) individuals from the assessment to their normal diet, viewpoints found since indicate ± SD. Data was basically examined because of the three-ways ANOVA that have pairwise comparison followed closely by Tukey’s post hoc attempt.

Relationship away from SBP philosophy along the whole list of urinary salt in order to potassium removal (Na + /K + ) proportion in salt sensitive and painful (n = 71) and you will sodium unwilling (letter = 119) individuals with losing weight intervention of one’s Losing weight Approaches to End Blood circulation pressure (DASH) (a) highest salt (HS), (Pearson’s Roentgen 2 for salt sensitive = 0.04 and you may salt resistant = 0.04) (b) low sodium (LS) eating plan, (Pearson’s R 2 to have salt sensitive = 0.02 and you will salt resistant = 0.00002).